| http://www.w3.org/ns/prov#value | - Said methods comprise expressing in a host cell (for e.g., a prokaryotic cell such as E. coli) an irnmunoglobulin light chain and a variant immunoglobulin heavy chain, said variant immunoglobulin heavy chain having a reduced ability to form a disulfide linkage, whereby efficiency of assembly of the variant heavy chain and said light chain is greater than the efficiency of assembly of a reference i
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