| http://www.w3.org/ns/prov#value | - Cis-acting exonic and intronic splicing regulatory elements (ESRs/ISRs), recognized by trans-acting factors such as SR and hnRNPs proteins, modulate exon selection and regulate alternative splicing (6,12).With 1.07 million copies, Alu elements are the most abundant repetitive element in the human genome, composing more than 10% of the genome (3,13).
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