| http://www.w3.org/ns/prov#value | - Ecstasy remains highly popular throughout the world, especially in North America, Western Europe and Oceania (United Nations Office on Drugs and Crimes 2008).Numerous animal studies support MDMA-induced long term serotonergic (5-HT) alterations through degeneration of presynaptic axon terminals and depletion of brain 5-HT upon exposure to MDMA of adequate magnitude and chronicity (Gibb et al. 1990
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